Discovery potential for Higgs bosons beyond the SM

The discovery potential of the CMS detector for the MSSM neutral and charged Higgs bosons at the LHC is presented based on studies with full detector simulation and event reconstruction of the principal discovery channels.Comment: Prepared for International Europhysics Conference on High Energy Physics (EPS-HEP2007), Manchester, England, 19-25 Jul 200

Heavy MSSM Higgs Bosons at CMS: "LHC wedge" and Higgs-Mass Precision

The search for MSSM Higgs bosons will be an important goal at the LHC. In order to analyze the search reach of the CMS experiment for the heavy neutral MSSM Higgs bosons, we combine the latest results for the CMS experimental sensitivities based on full simulation studies with state-of-the-art theoretical predictions of MSSM Higgs-boson properties. The experimental analyses are done assuming an integrated luminosity of 30 or 60 fb^-1. The results are interpreted as 5 \si discovery contours in MSSM M_A-tan_beta benchmark scenarios. Special emphasis is put on the variation of the Higgs mixing parameter mu. While the variation of mu can shift the prospective discovery reach (and correspondingly the ``LHC wedge'' region) by about Delta tan_beta= 10, the discovery reach is rather stable with respect to the impact of other supersymmetric parameters. Within the discovery region we analyze the accuracy with which the masses of the heavy neutral Higgs bosons can be determined. An accuracy of 1-4% should be achievable, depending on M_A and tan_beta.Comment: Talk given by G.W. at EPS07 (Manchester, July 2007) and talk given by S.H. at SUSY07 (Karlsruhe, July 2007). 4 pages, 2 figure

New Physics summary

We introduce the various contributions to the New Physics Session by identifying four main areas: Higgs-like signatures, supersymmetry, exotica and lepton flavour violation searches

Evaluation of an Internet Document Delivery Service

An Internet-based Document Delivery Service (DDS) has been developed within the framework of the CNR ( the Italian Research National Council) Project BiblioMIME, in order to take advantage of new Internet technologies and promote cooperation among CNR and Italian university libraries. Adopting such technologies changes the traditional organisation of DDS and may drastically reduce costs and delivery times. An information system managing DDS requests and monitoring the temporal evolution of the service has been implemented, running on the local-area network of a test-site library. It aims to track number and types of documents requested and received, user distribution, delivery times and types (surface mail, fax, Internet), to automate repetitive manual procedures and to deal with the various accounting methods used by other libraries. Transmission of documents is carried out by means of an e-mail/Web gateway system supporting document exchange via Internet, which assists receiving libraries in retrieving requested documents. This paper describes the architecture and main design features of the e-mail/Web gateway server (the BiblioMime server). This approach permits librarians to continue using e-mail service to send large documents, while resolving problems that users may encounter when downloading large size files with e-mail agents. The library operator sends the document as an attachment to the destination address; on fly the e-mail server extracts and saves the attachments in a web-server disk file and substitutes them with a new message part that includes an URL pointing to the saved document. The receiver can download these large objects by means of a user-friendly browser. We further discuss the data gathered during the triennium 1998-2000; this consists of about 5,000 DDS transactions per annum with 300 other Italian scientific and bio-medical libraries and commercial document suppliers. Use of the instruments described above allowed us to evaluate the performance of service "before" and "after" the use of Internet Document Delivery and to extract some critical data regarding DDS. Those include: a) libraries with which we have greater numbers of exchanges and their turnaround times; b) extraordinary reduction in costs and delivery times; c) the most frequently requested serial titles (allowing cost-effective decisions on new subscriptions); d) impact on DDS of library participation in consortia which allow user access to greater numbers of online serials

Determining the CP parity of Higgs bosons at the LHC in their tau decay channels

If neutral Higgs bosons will be discovered at the CERN Large Hadron Collider (LHC) then an important subsequent issue will be the investigation of their CP nature. Higgs boson decays into tau lepton pairs are particularly suited in this respect. Analyzing the three charged pion decay modes of the tau leptons and taking expected measurement uncertainties at the LHC into account, we show that the CP properties of a Higgs boson can be pinned down with appropriately chosen observables, provided that sufficiently large event numbers will eventually be available.Comment: Latex, 10 pages, 4 figure

Hemostatic Agents for the Management of Bleeding Risk Associated with Oral Anticoagulant Therapy Following Tooth Extraction: A Systematic Review

The occurrence of bleeding following dental extraction is a relatively common complication. A history of therapy with oral anticoagulants represents a major favoring factor, both in patients treated with vitamin K-antagonists (especially warfarin) and with direct oral anticoagulants (DOACs). Several local hemostatic measures can be applied to limit the bleeding risk in these patients. The aim of this systematic review is to evaluate what measures can be adopted to limit the bleeding risk following dental extractions in patients treated with oral anticoagulants. A literature search was performed, and 116 articles were retrieved. Titles and abstract analyses excluded 91 articles, and three more articles were excluded following full-text analysis. The systematic review was performed on 22 articles. Among the included articles, 20 studies reported on patients treated with warfarin, and two studies on patients treated with DOACs. The agents employed included local intra-alveolar agents, tranexamic acid, and PRF. The included studies were all at moderate/high risk of bias. Moreover, limited evidence is available on hemostasis in patients treated with DOACs. The available evidence hinders stating the superiority of one agent over the others. Further research is advised to increase the level of evidence of the application of hemostatic agents in patients treated with oral anticoagulants

Hybrid rescue technique after failure of a standard multibranched stent graft

A 78-year-old woman presented with type IIIC and IIID endoleaks after endovascular treatment for a thoracoabdominal aortic aneurysm. Mating between the ruptured segments of superior mesenteric artery stent graft was performed. After failed attempts at relining the right renal artery stent graft, a hybrid approach was used to connect the side branch to the target vessel: a stent graft was deployed into the side branch of the main graft and it was temporarily occluded with a balloon. After opening the sac, a stent graft was deployed into the right renal artery and the two stent grafts were connected with a running suture. Follow-up examination performed 1 month postoperatively by computed tomography imaging confirmed the effectiveness of this treatment

Autologous micro-fragmented adipose tissue for the treatment of diabetic foot minor amputations: A randomized controlled single-center clinical trial (MiFrAADiF)

Background: The diabetic foot ulcer (DFU) is one of the most prevalent complications of diabetes mellitus and often develops severe effects that can lead to amputation. A non-healing "minor" amputation often precedes a major amputation resulting in a negative impact on the function and quality of life of the patients. Stem cell-based therapies have emerged as a promising option to improve healing, and the adipose tissue is an abundant and easy to access source. The injection of autologous micro-fragmented adipose tissue at the amputation stump of a diabetic population undergoing a lower limb minor amputation was evaluated and compared with the standard care. Methods: In this randomized controlled trial with two arms (parallel assignment) and no masking, 114 patients undergoing a lower limb minor amputation were randomized to standard of care or to micro-fragmented adipose tissue injection prepared using a minimal manipulation technique (Lipogems®) in a closed system. Clinical outcomes were determined monthly up to 6 months. Primary endpoint of the study was the evaluation of the healing rate and time after the minor amputation. Secondary endpoints included the assessment of safety, feasibility, technical success, relapse rate, skin tropism, and intensity of pain. Results: At 6 months, 80% of the micro-fragmented adipose tissue-treated feet healed and 20% failed as compared with the control group where 46% healed and 54% failed (p = 0.0064). No treatment-related adverse events nor relapses were documented, and technical success was achieved in all cases. The skin tropism was improved in the treatment group, and the pain scale did not differ between the two groups. Conclusion: The results of this randomized controlled trial suggest that the local injection of autologous micro-fragmented adipose tissue is a safe and valid therapeutic option able to improve healing rate following minor amputations of irreversible DFU. The technique overcomes several stem cell therapy-related criticisms and its potential in wound care should be better evaluated and the therapeutic indications could be expanded. Trial registration: ClinicalTrials.gov number: NCT03276312. Date of registration: September 8, 2017 (retrospectively registered)

Kit didáctico para la enseñanza de sistemas embebidos

Este artículo presenta un modelo de herramienta didáctica para el abordaje de los sistemas digitales embebidos en cursos universitarios. Se comienza estudiando el estado del arte con una visión crítica, analizando las estrategias utilizadas en el ámbito profesional y académico. Se evalúan distintas alternativas para implementación, entre ellas el impacto que los dispositivos lógicos programables han producido en la disciplina. Finalmente se presentan algunas ideas para la construcción de una herramienta didáctica útil y eficiente.Red de Universidades con Carreras en Informática (RedUNCI